| Standard Scoring | ||
| 1 | Derrick Henry | DEN |
| 2 | Joe Mixon | @ NYJ |
| 3 | Saquon Barkley | JAC |
| 4 | D'Andre Swift | @ ARI |
| 5 | Kyren Williams | @ SEA |
| 6 | Jahmyr Gibbs | @ GB |
| 7 | Josh Jacobs | DET |
| 8 | James Cook | MIA |
| 9 | Ken Walker | LAR |
| 10 | Bijan Robinson | DAL |
| 11 | Breece Hall | HOU |
| 12 | Jonathan Taylor | @ MIN |
| 13 | Tyrone Tracy | WAS |
| 14 | Chase Brown | LV |
| 15 | Tony Pollard | NE |
| 16 | Alvin Kamara | @ CAR |
| 17 | De'Von Achane | @ BUF |
| 18 | Kareem Hunt | TB |
| 19 | David Montgomery | @ GB |
| 20 | Aaron Jones | IND |
| 21 | James Conner | CHI |
| 22 | Chuba Hubbard | NO |
| 23 | Cartavious Bigsby | @ PHI |
| 24 | Rhamondre Stevenson | @ TEN |
| 25 | Alexander Mattison | @ CIN |
| 26 | Nick Chubb | LAC |
| 27 | Austin Ekeler | @ NYG |
| 28 | Javonte Williams | @ BAL |
| 29 | J.K. Dobbins | @ CLE |
| 30 | Rico Dowdle | @ ATL |
| 31 | Bucky Irving | @ KC |
| 32 | Rachaad White | @ KC |
| 33 | Raheem Mostert | @ BUF |
| 34 | Tyler Allgeier | DAL |
| 35 | Jeremy McNichols | @ NYG |
| 36 | Travis Etienne | @ PHI |
| 37 | Zach Charbonnet | LAR |
| 38 | Ray Davis | MIA |
| 39 | Braelon Allen | HOU |
| 40 | Justice Hill | DEN |
| 41 | Zamir White | @ CIN |
| 42 | Roschon Johnson | @ ARI |
| 43 | Ty Chandler | IND |
| 44 | Emanuel Wilson | DET |
| 45 | Jerome Ford | LAC |
| 46 | Jaleel McLaughlin | @ BAL |
| 47 | Miles Sanders | NO |
| 48 | Jaylen Wright | @ BUF |
| 49 | Ty Johnson | MIA |
| 50 | Devin Singletary | WAS |
| PPR Scoring | ||
| 1 | Derrick Henry | DEN |
| 2 | Joe Mixon | @ NYJ |
| 3 | Saquon Barkley | JAC |
| 4 | Ken Walker | LAR |
| 5 | D'Andre Swift | @ ARI |
| 6 | Kyren Williams | @ SEA |
| 7 | Alvin Kamara | @ CAR |
| 8 | Jahmyr Gibbs | @ GB |
| 9 | Josh Jacobs | DET |
| 10 | Bijan Robinson | DAL |
| 11 | Breece Hall | HOU |
| 12 | James Cook | MIA |
| 13 | Jonathan Taylor | @ MIN |
| 14 | Tyrone Tracy | WAS |
| 15 | Chase Brown | LV |
| 16 | Tony Pollard | NE |
| 17 | De'Von Achane | @ BUF |
| 18 | Aaron Jones | IND |
| 19 | Kareem Hunt | TB |
| 20 | Chuba Hubbard | NO |
| 21 | David Montgomery | @ GB |
| 22 | James Conner | CHI |
| 23 | Cartavious Bigsby | @ PHI |
| 24 | Austin Ekeler | @ NYG |
| 25 | Alexander Mattison | @ CIN |
| 26 | Rhamondre Stevenson | @ TEN |
| 27 | Javonte Williams | @ BAL |
| 28 | Nick Chubb | LAC |
| 29 | Bucky Irving | @ KC |
| 30 | Rachaad White | @ KC |
| 31 | J.K. Dobbins | @ CLE |
| 32 | Rico Dowdle | @ ATL |
| 33 | Raheem Mostert | @ BUF |
| 34 | Tyler Allgeier | DAL |
| 35 | Zach Charbonnet | LAR |
| 36 | Justice Hill | DEN |
| 37 | Travis Etienne | @ PHI |
| 38 | Jeremy McNichols | @ NYG |
| 39 | Ray Davis | MIA |
| 40 | Braelon Allen | HOU |
| 41 | Jerome Ford | LAC |
| 42 | Zamir White | @ CIN |
| 43 | Miles Sanders | NO |
| 44 | Dare Ogunbowale | @ NYJ |
| 45 | Roschon Johnson | @ ARI |
| 46 | Jaleel McLaughlin | @ BAL |
| 47 | Ty Chandler | IND |
| 48 | Emanuel Wilson | DET |
| 49 | Ty Johnson | MIA |
| 50 | Jaylen Wright | @ BUF |